Preventing all the complications of hyperglycaemia: not a straightforward task

Aidan McElduff
Med J Aust 2016; 205 (4): . || doi: 10.5694/mja16.00726
Published online: 15 August 2016

Individualised multifactorial treatment strategies are required to optimise outcomes

Epidemiological studies have found positive relationships between measures of glycaemia and adverse fetal and maternal pregnancy outcomes,1 macrovascular disease2,3 and the microvascular complications of diabetes.2,3 The relationship between glycaemia and microvascular disease is more complicated, as there is an inflection point below which the risk is very low, but beyond which it rises sharply. The inflection point of the relationship between glycaemia values and the prevalence of retinopathy has been used to determine both the glucose tolerance test values and the glycated haemoglobin (HbA1c) level used to diagnose diabetes (see Figure 1 in reference 3).

  • Aidan McElduff

  • University of Sydney, Sydney, NSW

Competing interests:

No relevant disclosures.


remove_circle_outline Delete Author
add_circle_outline Add Author

Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Online responses are no longer available. Please refer to our instructions for authors page for more information.